2023614 · PROTEUS2 - is a web server designed to support comprehensive protein structure prediction and structure-based annotation. PROTEUS2 accepts either single sequences (for directed studies) or multiple sequences (for whole proteome annotation) and predicts the secondary and, if possible, tertiary structure of the query protein (s).
view morerompt-guided multi-task pre-training and fine-tuning framework. Through the prompt-guided multi-task pre-training, we learn multiple prompt signals to steer the model, c. lled PromptProtein, to focus on different levels of structures. We also design a prompt fine-tuning module to provide downstream tasks the on-demand flexi.
view more202344 · ABSTRACT Predicting protein function is a longstanding challenge that has significant scien-tific implications. The success of amino acid sequence-based learning methods depends on the relationship between sequence, structure, and function. However, recent advances in AlphaFold have led to highly accurate protein structure data becoming …
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view more2024120 · Bacteria use various defense systems to protect themselves from phage infection, and phages have evolved diverse counter-defense measures to overcome host defenses. Here, the authors use protein ...
view more2012518 · Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid ...
view more2023320 · Limitations of Alphafold2 structure prediction are addressed by including experimentally determined distance constraints.
view moreThis paper provides a comprehensive overview of recent protein structure prediction efforts and progress using various soft computing techniques. In molecular and computational biology, predicting the three-dimensional structure of a protein from its amino acid sequence has long been an outstanding goal. Soft computing techniques for solving protein …
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