20121221 · The release of PYY from intestinal endocrine cells is stimulated by intraluminal nutrients, lipids, short-chain fatty acids, glucose, amino-acids, and bile salts. PYY release can also be mediated via a neural reflex involving the vagus nerve, as well as by other gut neuroendocrine peptides such as vasoactive intestinal peptide (VIP), …
view more20131015 · Background and Purpose. l -glutamine (Gln) is an energy source for gastrointestinal (GI) epithelia and can stimulate glucagon-like peptide 1 (GLP-1) release from isolated enteroendocrine L-cells. GLP-1 and peptide YY (PYY) are co-secreted postprandially and both peptides have functional roles in glucose homeostasis and …
view more2016114 · Within the gastrointestinal tract, FFAR2 and 3 have been localized to enteroendocrine L cells [17]. These specialized gut cells secrete the anorectic hormone peptide YY (PYY) and the incretin glucagon-like peptide-1 (GLP-1) in response to luminal nutrients, such as sugars, amino acids, and long-chain fatty acids [17], [21], [22].
view more2019617 · In this regard, recent studies have confirmed a positive effect of PYY on beta-cell survival and overall function, linked to the activation of NPYR1s. 10, 11 Thus, PYY (1-36) has been shown to enhance the growth and survival of beta-cells, 8 ultimately leading to enhanced glycaemic control. 12 In agreement with this, the ablation of PYY-expressing …
view moreMajor Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin Kristoffer L. Egerod,* Maja S. Engelstoft ...
view more2022912 · PYY production is highest in enteroendocrine cells located in the distal intestine, mirroring the sites where high concentrations of short chain fatty acids (SCFAs) are produced by gut microbiota ...
view more201818 · Peptide-YY (PYY) and Glucagon-Like Peptide-1 (GLP-1) play important roles in the regulation of food intake and insulin secretion, and are of translational interest in the field of obesity and diabetes. PYY production is highest in enteroendocrine cells located in the distal intestine, mirroring the …
view more2006221 · G gust-positive cells (left) located in either the glandular or surface epithelium of the colon colocalized with PYY (middle) as shown in the merged image (overlay; right). The arrows point to representative cells that coexpressed G gust and PYY immunoreactivity. The insets show cells in the surface epithelium.
view more201411 · Gas dispersion measurements were conducted in three flotation cells: TankCell 1, TankCell e300 and TankCell e500. The measurements reported in this paper were carried out exclusively in two-phase ...
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